MSI, or Intracytoplasmic Morphologically Selected Sperm Injection, is an advanced fertility treatment designed to enhance sperm selection during IVF procedures. Unlike standard ICSI, IMSI uses high magnification to identify sperm with the best morphology and genetic quality, improving chances of fertilization and pregnancy.
When is IMSI Recommended?
- Several Unsuccessful Transfer Attempts
If you have experienced multiple failed embryo transfers during previous IVF or ICSI cycles, IMSI may offer a better chance by selecting higher-quality sperm. - Severe Teratozoospermia
Men with a high percentage of abnormally shaped sperm benefit from IMSI, as it allows embryologists to pick the healthiest sperm, increasing fertilization success. - Abnormal Sperm DNA Fragmentation
For patients showing altered or elevated sperm DNA fragmentation, IMSI helps by choosing sperm with lower DNA damage, supporting better embryo development. - Long-Term Unexplained Infertility
Couples struggling with infertility of unknown cause for an extended period might consider IMSI to enhance fertilization outcomes when other treatments have not succeeded. - Poor Outcomes After ICSI
If conventional ICSI results in low fertilization rates or poor embryo quality, IMSI is a valuable option to improve sperm selection precision and overall outcomes.
Conclusion
IMSI represents a major advancement in fertility treatments, particularly useful for challenging cases involving male infertility or prior IVF failures. By enabling selection of sperm with optimal morphology and minimal genetic damage, IMSI increases the likelihood of successful fertilization, embryo development, and pregnancy. Couples considering IMSI should discuss these specific indications and potential benefits with their fertility specialist to determine the best approach tailored to their needs.