Intrauterine insemination (IUI) is a frequently chosen fertility treatment designed to address several underlying causes of infertility in both men and women. It is minimally invasive, cost-effective, and often used before considering more advanced treatments like IVF.
Here are the main indications for IUI:
- Mild Male Factor Infertility
IUI is often recommended when there are mild abnormalities in sperm count, motility, or morphology. By preparing and concentrating sperm before placement in the uterus, IUI helps increase the chances of fertilization in cases of mildly compromised semen parameters. - Inability to Have Penetrative Sex
Couples who are unable to have vaginal intercourse—such as those affected by vaginismus, erectile dysfunction, or anatomical issues—may benefit from IUI, as it bypasses the need for penetrative sex to achieve pregnancy. - Repeated Ovulation Induction Failure (>6 Cycles)
Women who have undergone six or more unsuccessful cycles of ovulation induction (using medications to stimulate egg release) are often considered for IUI as a next step, especially if ovulation is occurring but conception hasn’t happened. - Unexplained Infertility
When the cause of infertility cannot be identified despite extensive evaluation, IUI is frequently recommended. It increases the likelihood of sperm meeting the egg by bypassing potential subtle barriers. - Mild Endometriosis and Mild PCOS
IUI can be helpful for women with mild endometriosis or mild polycystic ovary syndrome (PCOS), especially when combined with ovulation induction medication. It is less effective in moderate to severe cases of endometriosis but may improve outcomes in milder disease.
Conclusion
IUI is a versatile treatment with wide-ranging indications, including mild male and female factor infertility, inability to have intercourse, unexplained infertility, and certain hormonal or anatomical conditions. Consultation with a fertility specialist helps determine if IUI is the most suitable next step in your fertility journey.