Recurrent pregnancy loss (RPL) can occur due to various reasons, including genetic, anatomical, hormonal, immunological, and infectious causes.
Among infections, Bacterial Vaginosis (BV) stands out as the most frequently associated infection with spontaneous abortions and premature births.
Bacterial Vaginosis and Pregnancy Loss
- Bacterial Vaginosis is characterized by an imbalance in the normal vaginal flora, leading to an overgrowth of harmful bacteria.
- BV has been linked to increased risks of miscarriage, particularly in the first trimester, and premature labor.
- The infection can cause inflammation and changes in the vaginal and uterine environment that compromise pregnancy viability.
Other Infectious Agents in Recurrent Pregnancy Loss
Although BV is the most common, other infections may also play a role, including:
- Ureaplasma urealyticum
- Mycoplasma hominis
- Chlamydia trachomatis
- Listeria monocytogenes
- Herpes simplex virus (HSV)
These infections can contribute to miscarriage by disrupting the uterine environment, inducing inflammation, or affecting the placenta.
Conclusion
Bacterial Vaginosis is the most frequently observed infection associated with recurrent pregnancy loss, especially spontaneous abortions and premature birth. Screening and treatment of BV and other infections are important components of evaluating couples with RPL to improve pregnancy outcomes.