For intrauterine insemination (IUI) to be successful, the sperm sample needs to meet certain quality and quantity standards, especially regarding the concentration of motile sperm.
Recommended Sperm Concentration for IUI:
- Minimum total sperm concentration: At least 8 to 10 million motile sperm per milliliter after processing (sperm washing) is considered ideal for IUI success.
- Before processing, the original semen sample ideally has around 15 million sperm per milliliter or more to ensure adequate motile sperm remain after washing.
- Sperm motility (the percent of moving sperm) should be at least 30-40% progressive motility to maximize chances.
- Total motile sperm count (TMSC) above 5 million is generally the lower threshold below which IUI success rates decline significantly.
Why is Concentration Important?
- The process of washing removes seminal plasma, dead sperm, and debris, concentrating the most motile and healthy sperm for insemination.
- A higher number of motile sperm increases the likelihood that sperm will reach and fertilize the egg.
- Sperm concentration and motility together influence fertilization potential and pregnancy success.
If Sperm Count is Low?
- If motile sperm concentration is below 1 million after washing, chances of success drop significantly.
- In such cases, other assisted reproductive techniques like IVF with ICSI might be recommended.
Conclusion
For effective IUI, aim for a total motile sperm concentration of at least 8-10 million/ml after sperm preparation. This threshold balances the chance of conception with the least invasiveness. Consultation with a fertility specialist ensures personalized evaluation and treatment planning based on these parameters.