Idiopathic infertility male: A Fertility guide to Male patients

Idiopathic male infertility (UMI) means couples cannot conceive after one year of regular sexual intercourse. The latest statistics show that, on average, 4-17% of couples seek medical treatment for infertility. But the accurate picture might be more than this based on the increasing stress, tension, and fast-paced lifestyle. Out of all these cases, the male factor is solely and partially implicated in 20-50% of cases. Fertility is one of the fields where there is constant research and advancement. But even after many modern technologies, a significant subset of these subfertile men is classified as having idiopathic male infertility (UMI). To diagnose a male as UMI, they should have normal results in semen analysis, normal history, and physical examination, and when female factor infertility has been ruled out. The average incidence of idiopathic infertile males is approximately 15%. 

Why is it difficult for idiopathic infertility males to conceive?

  • Presence Of Anti-Sperm Antibodies
  • Sperm DNA Damage
  • Elevated Levels Of Reactive Oxygen Species (Ros)
  • Sperm Dysfunction
  • Unexplained Female Factor Infertility 
  • Coital Factors such as inappropriate timing of intercourse
  • Erectile Dysfunction
  • Anejaculation.
  • Low semen quality. The quality do semen is reduced due to 
    • Anti-sperm antibodies
    • Sperm DNA damage
    • Elevated levels of reactive oxygen species (ROS)
    • Sperm dysfunction
  • Both partners might be infertile or sub-fertile, so the couple is infertile in a combination
  • Immunological or genetic

In idiopathic infertile males, there is a chance of natural conception in the next 1-2 years if they continue to have fertility-focused intercourse. 

Diagnosis of Idiopathic Infertility in male 

At first, the fertility specialist will do an exhaustive recording of the patient’s medical history and physical examination. If the semen analysis is fine, one should focus on the history of previous fertility, infertility duration, frequent miscarriages, congenital abnormalities in previous pregnancies, and medications. The fertility specialist will collect the detailed coital history of both partners and collect info about their inappropriate coital technique, infrequent intercourse, and inappropriate timing of the intercourse. 

Post the physical examination, the focus shifts towards assessing psychological stress. Out of the many issues with stress, infertility is one of the main ones. Due to prolonged stress, sperm quality reduces and increases the likelihood of depression, anxiety, or cardiovascular diseases. If the male already has infertility issues, it gets worse with stress, and the sexual life gets affected. Men usually deal less with their emotions due to reasons such as culture, stigma, and personality characteristics, and hence less attention is devoted to the effects of infertility. Therefore, at ZIVA fertility clinics, stress and stress management techniques are provided for both men and women. 

Idiopathic Male Infertility Treatments

Prevention: Maintain a healthy lifestyle, do not smoke or drink alcohol and do some sport activity at least twice a week for an hour.

Self-therapy:Reactive oxygen species (ROS) are a crucial factor in male infertility. Antioxidants are known to oppose the effects of ROS on at least one of the semen parameters, and the most significant impact was determined on sperm motility. The antioxidants known to work are vitamin E, vitamin C, selenium, CoQ10, N-acetyl-cysteine, L-carnitine, and zinc, and their favourable effect was confirmed.

Psychotherapy: In idiopathic infertile men, treating their psychological issues is essential. One should seek counselling individually or as a couple if there is an underlying cause of male idiopathic infertility. The counsellor working with a couple must strive to establish open communication within the couple. They should do stress management therapy, identify stress points and improve the couples’ relationship. Once the psychological blocks are removed, their sexual life improves, so the chances of conception are high. 

Medication: Since the cause of infertility is not accurately determined in idiopathic infertility, there is no specific prescribed medication that might do the magic. Based on the history of the patient and their intercourse habits, the fertility specialist will make a case-by-case decision.

Surgical therapy: No known surgical treatments are available for idiopathic male infertility.

Assisted reproduction for Idiopathic Infertility 

ICSI combined with IVF will help solve the problem of unexplained male infertility. In an ICSI and IVF combination, many hurdles in the oath of natural pregnancy are bypassed. Barriers like dysfunctional sperm are overcome in this method. If the pregnancy is achieved with such dysfunctional sperm, there might be a risk that the same infertility traits may pass on to the offspring.

If one has idiopathic pregnancy, they don’t have to lose all hope of achieving natural pregnancy. We offer both medical and psychological help for idiopathic infertile males. Please be courageous and, with your partner, visit us at ZIVA fertility Clinics at all convenient locations in Hyderabad. Please visit our website Fertility Hospital Hyderabad | Fertility Clinic Near me | Ziva IVF Center ( or contact us at +91-9100002737, +91-9392834024 and